
In rare cases, ACTIMMUNE can cause severe allergic reactions and/or rash. Your doctor should monitor your liver function every 3 months, and monthly in children under 1 year. Taking ACTIMMUNE may cause reversible changes to your liver function, particularly in patients less than 1 year old. This effect, which can be severe, is usually reversible when the drug is discontinued or the dose is reduced. These symptoms are usually reversible within a few days upon dose reduction or discontinuation of therapy.īone marrow function may be suppressed with ACTIMMUNE, and decreased production of cells important to the body may occur. What warnings should I know about ACTIMMUNE?Īt high doses, ACTIMMUNE can cause (flu-like) symptoms, which may worsen some pre-existing heart conditions.ĪCTIMMUNE may cause decreased mental status, walking disturbances, and dizziness, particularly at very high doses. coli derived products, or any ingredients contained in the product. When should I not take ACTIMMUNE?ĭon't use ACTIMMUNE if you are allergic to interferon-gamma, E. SMO is a genetic disorder that affects normal bone formation and is usually diagnosed in the first few months after birth. CGD is often treated (though not cured) with antibiotics, antifungals, and ACTIMMUNE.ĪCTIMMUNE is also used to slow the worsening of severe, malignant osteopetrosis (SMO). CGD is a genetic disorder, usually diagnosed in childhood, that affects some cells of the immune system and the body's ability to fight infections effectively. The FDA-approved product labeling can be found at or 1-86.What is ACTIMMUNE ® (Interferon gamma-1b) used for?ĪCTIMMUNE ® is part of a drug regimen used to treat Chronic Granulomatous Disease, or CGD. To learn more, talk about ACTIMMUNE with your healthcare provider or pharmacist. The risk information provided here is not comprehensive. You are encouraged to report negative side effects of prescription drugs to the FDA. Tell your doctor about all other medications you are taking.Īvoid taking ACTIMMUNE at the same time as a vaccination. Some drugs may interact with ACTIMMUNE to potentially increase the risk of damage to your heart or nervous system, such as certain chemotherapy drugs. What other medications might interact with ACTIMMUNE? Acetaminophen may be helpful in preventing fever and headache. Bedtime administration of ACTIMMUNE may help reduce some of these symptoms. The most common side effects with ACTIMMUNE are “flu-like” symptoms such as fever, headache, chills, muscle pain, or fatigue, which may decrease in severity as treatment continues. Your doctor will monitor these cells with blood tests at the beginning of therapy and at 3-month intervals on ACTIMMUNE therapy

What should I tell my healthcare provider?īe sure to tell your doctor about all the medications you are taking. If you experience a serious reaction to ACTIMMUNE, discontinue it immediately and contact your doctor or seek medical help.


When should I not take ACTIMMUNE?ĭon’t use ACTIMMUNE if you are allergic to interferon-gamma, E coli-derived products, or any ingredients contained in the product. ACTIMMUNE is also used to slow the worsening of severe, malignant osteopetrosis (SMO).
